Plinest 2ml An Advanced Polynucleotide Skin Booster
Plinest 2ml by Mastelli is a professional polynucleotide-based injectable skin rejuvenation treatment, formulated using PN-HPT™ (Polynucleotides – Highly Purified Technology). Designed for intradermal use, Plinest helps support the skin’s natural regenerative processes while improving the appearance of skin texture, elasticity, firmness and hydration.
Plinest contains 40mg of highly purified polynucleotides in 2ml, supplied as a sterile, pre-filled syringe. The polynucleotide formulation is designed to provide skin-priming and regenerative support, making Plinest suitable for professional protocols targeting signs of skin ageing and compromised skin quality.
Key Benefits of Plinest
- Contains 40mg PN-HPT™ in 2ml
- Highly purified long-chain polynucleotide formulation
- Supports skin regeneration and extracellular matrix remodelling
- Helps improve skin elasticity, firmness and texture
- Supports hydration and overall skin quality
- Designed for skin showing signs of ageing
- Suitable for professional skin-priming protocols
- Can be incorporated into combination aesthetic treatment programmes
Treatment Areas
Plinest is designed for professional intradermal treatment of areas including:
- Face
- Neck
- Décolletage
- Areas affected by reduced elasticity, skin laxity or compromised texture
It may also be incorporated into personalised professional protocols for areas with a greater fibrous component, such as certain scars and stretch marks. Treatment suitability should always be determined by an appropriately qualified medical professional.
How Plinest Works
Plinest uses PN-HPT™ technology, developed by Mastelli to produce highly purified polynucleotides. Polynucleotides are DNA-derived molecules used in regenerative aesthetic medicine to support the skin’s natural repair and remodelling processes.
Clinical information supplied for Plinest reports improvements in skin texture, hydration and elasticity following a course of intradermal treatments. In the cited clinical evaluation, more than 90% of subjects demonstrated overall clinical improvement in skin texture and reduction of superficial fine lines.
Product Information
Brand: Mastelli
Product: Plinest
Product type: Polynucleotide injectable / Class III medical device
Formulation: PN-HPT™ polynucleotides
Concentration: 40mg / 2ml
Presentation: 1 × 2ml pre-filled syringe
Needles: 2 × 30G ½ needles
Administration: Intradermal
Manufacturer: Mastelli, Italy
Professional Use
Plinest 2ml is intended for professional use only and should be administered by an appropriately qualified healthcare professional in accordance with the manufacturer’s current instructions for use, applicable regulations and appropriate clinical protocols.
Please check the product packaging and current manufacturer documentation before use.



